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A Brief Discussion on Clinical Pharmacology Research of CAR-T Drugs
Public date:2024-10-11 09:23:38 Views:
Chimeric Antigen Receptor T-cell Immunotherapy, abbreviated as CAR-T cell therapy, belongs to adoptive immune cell therapy, which modifies T cells in vitro through genetic engineering to enable T cells to specifically recognize tumor antigens and kill tumor cells.
This article will use the FDA clinical pharmacology approval report as a reference to discuss the clinical pharmacology characteristics of approved CAR-T drugs from the aspects of cell dynamics, pharmacodynamics, and exposure effect relationship, and summarize the clinical pharmacology research strategies for this type of drug.
